Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.
Identifieur interne : 000566 ( Main/Exploration ); précédent : 000565; suivant : 000567Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.
Auteurs : Svetlana Shcherbik [États-Unis] ; Nicholas Pearce [États-Unis] ; Amanda Balish [États-Unis] ; Joyce Jones [États-Unis] ; Sharmi Thor [États-Unis] ; Charles Todd Davis [États-Unis] ; Melissa Pearce [États-Unis] ; Terrence Tumpey [États-Unis] ; David Cureton [États-Unis] ; Li-Mei Chen [États-Unis] ; Julie Villanueva [États-Unis] ; Tatiana L. Bousse [États-Unis]Source :
- PloS one [ 1932-6203 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Furets (immunologie), Furets (virologie), Génome viral, Infections à Orthomyxoviridae (), Infections à Orthomyxoviridae (immunologie), Instabilité du génome, Modèles animaux de maladie humaine, Russie, Sous-type H7N9 du virus de la grippe A (génétique), Sous-type H7N9 du virus de la grippe A (immunologie), Vaccins antigrippaux (génétique), Vaccins antigrippaux (immunologie), Vaccins atténués (génétique), Vaccins atténués (immunologie), Virus recombinants (génétique), Virus recombinants (immunologie).
- MESH :
- génétique : Sous-type H7N9 du virus de la grippe A, Vaccins antigrippaux, Vaccins atténués, Virus recombinants.
- immunologie : Furets, Infections à Orthomyxoviridae, Sous-type H7N9 du virus de la grippe A, Vaccins antigrippaux, Vaccins atténués, Virus recombinants.
- virologie : Furets.
- Animaux, Génome viral, Infections à Orthomyxoviridae, Instabilité du génome, Modèles animaux de maladie humaine, Russie.
English descriptors
- KwdEn :
- Animals, Disease Models, Animal, Ferrets (immunology), Ferrets (virology), Genome, Viral, Genomic Instability, Influenza A Virus, H7N9 Subtype (genetics), Influenza A Virus, H7N9 Subtype (immunology), Influenza Vaccines (genetics), Influenza Vaccines (immunology), Orthomyxoviridae Infections (immunology), Orthomyxoviridae Infections (prevention & control), Reassortant Viruses (genetics), Reassortant Viruses (immunology), Russia, Vaccines, Attenuated (genetics), Vaccines, Attenuated (immunology).
- MESH :
- chemical , genetics : Influenza Vaccines, Vaccines, Attenuated.
- chemical , immunology : Vaccines, Attenuated.
- geographic : Russia.
- genetics : Influenza A Virus, H7N9 Subtype, Reassortant Viruses.
- immunology : Ferrets, Influenza A Virus, H7N9 Subtype, Influenza Vaccines, Orthomyxoviridae Infections, Reassortant Viruses.
- prevention & control : Orthomyxoviridae Infections.
- virology : Ferrets.
- Animals, Disease Models, Animal, Genome, Viral, Genomic Instability.
Abstract
Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segments from wild type influenza viruses to induce protective immune responses and the six internal genes from Master Donor Viruses (MDV) to provide temperature sensitive, cold-adapted and attenuated phenotypes.
DOI: 10.1371/journal.pone.0138951
PubMed: 26405798
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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Battelle, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Battelle, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Pearce, Nicholas" sort="Pearce, Nicholas" uniqKey="Pearce N" first="Nicholas" last="Pearce">Nicholas Pearce</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Battelle, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Battelle, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Balish, Amanda" sort="Balish, Amanda" uniqKey="Balish A" first="Amanda" last="Balish">Amanda Balish</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Joyce" sort="Jones, Joyce" uniqKey="Jones J" first="Joyce" last="Jones">Joyce Jones</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Thor, Sharmi" sort="Thor, Sharmi" uniqKey="Thor S" first="Sharmi" last="Thor">Sharmi Thor</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Davis, Charles Todd" sort="Davis, Charles Todd" uniqKey="Davis C" first="Charles Todd" last="Davis">Charles Todd Davis</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Pearce, Melissa" sort="Pearce, Melissa" uniqKey="Pearce M" first="Melissa" last="Pearce">Melissa Pearce</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Tumpey, Terrence" sort="Tumpey, Terrence" uniqKey="Tumpey T" first="Terrence" last="Tumpey">Terrence Tumpey</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Cureton, David" sort="Cureton, David" uniqKey="Cureton D" first="David" last="Cureton">David Cureton</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Atlanta Research and Education Foundation, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America; Atlanta Research and Education Foundation, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Li Mei" sort="Chen, Li Mei" uniqKey="Chen L" first="Li-Mei" last="Chen">Li-Mei Chen</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Villanueva, Julie" sort="Villanueva, Julie" uniqKey="Villanueva J" first="Julie" last="Villanueva">Julie Villanueva</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author><author><name sortKey="Bousse, Tatiana L" sort="Bousse, Tatiana L" uniqKey="Bousse T" first="Tatiana L" last="Bousse">Tatiana L. Bousse</name><affiliation wicri:level="1"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea><wicri:noRegion>GA</wicri:noRegion></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Ferrets (immunology)</term><term>Ferrets (virology)</term><term>Genome, Viral</term><term>Genomic Instability</term><term>Influenza A Virus, H7N9 Subtype (genetics)</term><term>Influenza A Virus, H7N9 Subtype (immunology)</term><term>Influenza Vaccines (genetics)</term><term>Influenza Vaccines (immunology)</term><term>Orthomyxoviridae Infections (immunology)</term><term>Orthomyxoviridae Infections (prevention & control)</term><term>Reassortant Viruses (genetics)</term><term>Reassortant Viruses (immunology)</term><term>Russia</term><term>Vaccines, Attenuated (genetics)</term><term>Vaccines, Attenuated (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Furets (immunologie)</term><term>Furets (virologie)</term><term>Génome viral</term><term>Infections à Orthomyxoviridae ()</term><term>Infections à Orthomyxoviridae (immunologie)</term><term>Instabilité du génome</term><term>Modèles animaux de maladie humaine</term><term>Russie</term><term>Sous-type H7N9 du virus de la grippe A (génétique)</term><term>Sous-type H7N9 du virus de la grippe A (immunologie)</term><term>Vaccins antigrippaux (génétique)</term><term>Vaccins antigrippaux (immunologie)</term><term>Vaccins atténués (génétique)</term><term>Vaccins atténués (immunologie)</term><term>Virus recombinants (génétique)</term><term>Virus recombinants (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Influenza Vaccines</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Russia</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H7N9 Subtype</term><term>Reassortant Viruses</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H7N9 du virus de la grippe A</term><term>Vaccins antigrippaux</term><term>Vaccins atténués</term><term>Virus recombinants</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Furets</term><term>Infections à Orthomyxoviridae</term><term>Sous-type H7N9 du virus de la grippe A</term><term>Vaccins antigrippaux</term><term>Vaccins atténués</term><term>Virus recombinants</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Ferrets</term><term>Influenza A Virus, H7N9 Subtype</term><term>Influenza Vaccines</term><term>Orthomyxoviridae Infections</term><term>Reassortant Viruses</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Furets</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Ferrets</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Genome, Viral</term><term>Genomic Instability</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Génome viral</term><term>Infections à Orthomyxoviridae</term><term>Instabilité du génome</term><term>Modèles animaux de maladie humaine</term><term>Russie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segments from wild type influenza viruses to induce protective immune responses and the six internal genes from Master Donor Viruses (MDV) to provide temperature sensitive, cold-adapted and attenuated phenotypes.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Shcherbik, Svetlana" sort="Shcherbik, Svetlana" uniqKey="Shcherbik S" first="Svetlana" last="Shcherbik">Svetlana Shcherbik</name></noRegion><name sortKey="Balish, Amanda" sort="Balish, Amanda" uniqKey="Balish A" first="Amanda" last="Balish">Amanda Balish</name><name sortKey="Bousse, Tatiana L" sort="Bousse, Tatiana L" uniqKey="Bousse T" first="Tatiana L" last="Bousse">Tatiana L. Bousse</name><name sortKey="Chen, Li Mei" sort="Chen, Li Mei" uniqKey="Chen L" first="Li-Mei" last="Chen">Li-Mei Chen</name><name sortKey="Cureton, David" sort="Cureton, David" uniqKey="Cureton D" first="David" last="Cureton">David Cureton</name><name sortKey="Davis, Charles Todd" sort="Davis, Charles Todd" uniqKey="Davis C" first="Charles Todd" last="Davis">Charles Todd Davis</name><name sortKey="Jones, Joyce" sort="Jones, Joyce" uniqKey="Jones J" first="Joyce" last="Jones">Joyce Jones</name><name sortKey="Pearce, Melissa" sort="Pearce, Melissa" uniqKey="Pearce M" first="Melissa" last="Pearce">Melissa Pearce</name><name sortKey="Pearce, Nicholas" sort="Pearce, Nicholas" uniqKey="Pearce N" first="Nicholas" last="Pearce">Nicholas Pearce</name><name sortKey="Thor, Sharmi" sort="Thor, Sharmi" uniqKey="Thor S" first="Sharmi" last="Thor">Sharmi Thor</name><name sortKey="Tumpey, Terrence" sort="Tumpey, Terrence" uniqKey="Tumpey T" first="Terrence" last="Tumpey">Terrence Tumpey</name><name sortKey="Villanueva, Julie" sort="Villanueva, Julie" uniqKey="Villanueva J" first="Julie" last="Villanueva">Julie Villanueva</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26405798" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |